July 21, 2010

Sebastian E. Gutierrez-Maldonado

Position title: Postdoctoral Researcher

Education

  • Universidad Andrés Bello, Chile; PhD in Biotechnology; 2013-2018.
    • Research Topics: Solid-Supported Membranes, Bionanotechnology, Biosensors, Molecular Dynamics.
    • Thesis Title: Theoretical-experimental design and characterization of a biosilicon nanointerface for biotechnological applications.
    • Supervisor: Dr. Tomas Perez-Acle.
  • Pontificia Universidad Católica de Chile, Chile; Biochemist (Professional degree); 2010-2012.
  • Pontificia Universidad Católica de Chile, Chile; BSc in Biochemistry; 2004-2009.

Positions and Employment

  • 2018 – up to date: Postdoctoral Researcher, Computational Biology Lab (DLab), Fundación Ciencia & Vida, Santiago, Chile.
  • 2013 – 2018: Graduate Student, Computational Biology Lab (DLab), Fundación Ciencia & Vida, Santiago, Chile.

Areas of interest
Structural Biology, Bionanotechnology, Membrane Proteins, GPCRs, Knotted Proteins, Molecular Dynamics, Structure-Based Models.

Current research
Determining the key interactions required for GPCR heterodimerization.

Work email address:
Personal email address: 

Peer-reviewed publications

  1. Slater PG*, Gutierrez-Maldonado SE*, Gysling K, Lagos CF. “Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor” (2018), Frontiers in Endocrinology, 9:43.
  2. Gutierrez-Maldonado SE, Garate JA, Retamal MJ, Cisternas MA, Volkmann UG, Perez-Acle T. “Accessing the structural and thermodynamic properties of ultra-thin layers of C32 adsorbed on a SiO2 surface” (2017), Chemical Physics Letters, 674:64.
  3. Vargas AA, Cisterna BA, Saavedra-Leiva F, Urrutia C, Cea LA, Vielma AH, Gutierrez-Maldonado SE, Martin AJM, Pareja-Barrueto C, Escalona Y, Schmachtenberg O, Lagos CF, Perez-Acle T, Sáez JC. “On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells” (2017), Frontiers in Physiology, 8:38.
  4. Retamal MJ, Cisternas MA, Gutierrez-Maldonado SE, Perez-Acle T, Seifert B, Busch M, Huber P, Volkmann UG. “Towards bio-silicon interfaces: Formation of an ultra-thin self-hydrated artificial membrane composed of dipalmitoylphosphatidylcholine (DPPC) and chitosan deposited in high vacuum from the gas- phase” (2014), Journal of Chemical Physics, 141:104201.
  5. Abarca F, Gutierrez-Maldonado SE, Parada P, Martinez P, Maass A, Perez-Acle T. “Insights on the structure and stability of Licanantase: a trimeric acid-stable coiled-coil lipoprotein from Acidithiobacillus thiooxidans” (2014), PeerJ, 2:e457.

Sebastian E. Gutierrez-Maldonado

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